Chloroquine – Medical Facts You Should Know About This Anti Malarial Drug
Chloroquine Phosphate is a 4 aminoquinoline drug that is used in the treatment and prevention of Malaria. The drug was originally discovered by Hans Andersag in the year 1934 and his co-workers at the Bayer’s laboratory. The drug was named as Resochin for the first time; the drug was ignored for more than a decade for its toxicity and adverse effects. Only during the World War II it was approved by the government of US and the drug has been into clinical practice from the year 1947.
Chloroquine prevents the multiplication of malarial parasites in the blood and removes some species of the parasite from the liver. Sometimes the drug has to be taken as a prophylactic measure when one gets exposed to malaria prone areas.
How to use Chloroquine:
Chloroquine phosphate is available in tablet form for oral intake. In adults the drug is used once a week for prophylaxis. For acute attacks of malaria in adults, one dose of the drug is taken immediately followed by half the dose of the drug within next 6-8 hours and again half the dose once a day for the next 2 days.
To prevent and treat malaria in children, the dosage of the drug is calculated based on the weight of the baby. It is important to consume the drug with food as Chloroquine phosphate could upset the stomach. It is paramount to use the drug as directed and never to overdose or under dose without medical advice.
Precautions and Contraindications of the drug:
It is important to notify the physician if a person is allergic to the components of the drug. Chloroquine could react with drug such as cimetidine, isoniazid, Gaviscon, Theumatrex, Rifadin and some herbal products. People with liver disease, hearing disabilities, psoriasis, vision changes and alcoholism should refrain from using the drug without close medical supervision.
The drug is not indicated during pregnancy and while nursing the baby and it is important to inform the doctor on the same before starting to use the drug.
Top Benefits of Chloroquine:
• It is best used in the treatment of malaria. The drug in used in mass drug administration to enhance resistance for the parasite.
• The drug supresses the immune system and is indicated in some auto-immune disorders such as rheumatoid arthritis and lupus.
• The drug is under investigation for its potentiality to behave as an anti-viral agent in Chikungunya fever.
• Chloroquine is been investigated for its chemo sensitizing properties to be used in anti-cancer strategies for humans.
• The chemical component is used to treat amoebiasis in children.
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